From Clemson Extension Plant Pathologist Tony Keinath.

During the 2019 Cantaloupe Disease Survey, Alternaria leaf blight has been found in several fields. It was more common in fields that had not been sprayed recently than in fields sprayed on a regular schedule. It also was found in a field rotated only one year out of cantaloupe.

Alternaria leaf blight lesions on cantaloupe leaf.

The FRAC Group 11 fungicides (Cabrio, Quadris, Flint) are the recommended fungicides. Although the gummy stem blight fungus is resistant to this group of fungicides, they still are very effective against Alternaria leaf blight on cantaloupe and anthracnose on watermelon.